Manipal Hospital, Yelahanka, Bengaluru has become the first hospital in India to install the Elekta Evo, an advanced AI-enabled adaptive CT-Linac platform that brings Online Adaptive Radiotherapy (oART) into routine clinical practice. The new technology allows radiation treatment plans to be modified in real time based on daily changes in a patient’s anatomy, helping improve treatment precision and patient outcomes.
The installation comes after Elekta showcased the Evo platform during AROICON 2025, India’s leading radiation oncology conference held in Kolkata. The hospital has already begun using the system to treat patients requiring advanced radiation therapy.
The need for such technologies is increasing as India’s cancer burden continues to grow. According to the Indian Council of Medical Research (ICMR), nearly 1.46 million people are diagnosed with cancer each year in the country. With many patients presenting at advanced stages of the disease, precision-driven radiation therapy has become increasingly important for achieving better clinical outcomes while protecting healthy tissue.
At Manipal Hospital, the new platform has strengthened the hospital’s radiation oncology services by enabling doctors to tailor treatment throughout the therapy cycle. The technology allows clinicians to review anatomical changes before each session and adjust radiation delivery accordingly, making personalised treatment more practical without affecting clinical efficiency.
The hospital has already completed its first online adaptive radiotherapy treatment using Elekta Evo on a patient with locally advanced rectal cancer. Following neoadjuvant chemoradiotherapy, the patient experienced minimal radiation-related side effects, demonstrating the potential of adaptive treatment to accurately target tumours while reducing radiation exposure to nearby healthy organs.
Feras Al Hasan, Head of Region TIMEA at Elekta, said, “The installation of India’s first Elekta Evo at Manipal Hospital marks an important milestone in expanding access to adaptive radiation therapy in the country. Since introducing Evo at AROICON last year, our ambition has been to make this next generation of precision radiation therapy available to clinicians treating increasingly complex cancers. By combining AI-enhanced imaging with online adaptive capabilities on a highly versatile CT-Linac platform, Evo enables clinicians to make more informed treatment decisions throughout a patient’s care journey. We are proud to partner with Manipal Hospital in bringing this innovation to India and reaffirm our commitment to advancing high-quality cancer care across the region.”
The Elekta Evo platform combines Iris™ high-definition AI imaging with online and offline adaptive radiotherapy capabilities, allowing clinicians to visualise tumours and surrounding organs with greater clarity. The system also supports multiple radiation therapy techniques through a single platform, helping deliver accurate doses while limiting unnecessary radiation to healthy tissues.
Adaptive Radiotherapy (ART) differs from conventional radiation therapy by allowing treatment plans to be updated whenever changes occur in a patient’s anatomy or tumour during the treatment course. Elekta Evo integrates Elekta ONE® Online software with AI-assisted contouring, faster dose calculations and distributed treatment planning, enabling quicker and more efficient clinical decision-making.
Sharing the hospital’s early experience with the technology, Dr. Vikram Maiya, Lead Consultant – Radiation Oncology, Manipal Hospital, Yelahanka, said, “At Manipal Hospital, we are committed to bringing the latest advances in cancer care to our patients. Becoming the first hospital in India to install Elekta Evo reinforces that commitment. The platform enables our radiation oncology teams to adapt treatment to changes in a patient’s anatomy during therapy, supporting more individualised treatment decisions while enhancing our ability to deliver personalised, high-quality cancer care. We have already seen its clinical value in patients undergoing online adaptive radiotherapy, where daily treatment adaptation has helped achieve precise tumor targeting while minimising radiation exposure to healthy tissues. Our initial experience across rectal, cervical and prostate cancer patients has been encouraging, with treatments progressing well and minimal side effects observed so far.”
Currently, Manipal Hospital is using the Elekta Evo system to treat patients with rectal, cervical and prostate cancers through online adaptive radiotherapy. Initial clinical observations indicate that patients have tolerated the treatment well, with minimal treatment-related side effects reported during the ongoing therapy.
The introduction of India’s first Elekta Evo system marks an important advancement in the country’s radiation oncology landscape. By combining AI-powered imaging with adaptive treatment planning, Manipal Hospital is expanding access to more precise, personalised cancer care while supporting better treatment accuracy and improved patient experiences.
(Photo courtesy: manipalhospitals.com)